The Vascular Action of Pilocarpine, Eserine

relative cutaneous anergy often present in animals and man with inflammatory tuberculous lesions of the eye. This concept of the pathogenesis of a tuberculous lesion offers' obvious points for therapeutic attack on the disease. The first of these is enhancement of immunity, and nothing specific has been done as yet to stimulate local resistance artificially. The second is removal of the fatal tissue hypersensitivity, and this can usually be accomplished by the use of tuberculin as a desensitizing agent, and has a distinctly beneficial effect on the clinical course of the lesion. The third is the direct attack on the tubercle bacilli, and in streptomycin and promizole combined, we have a powerful weapon to this end. Doubtless other better' antibiotics and sulphones will be found, but at present this combination appears the best available.